The earliest settlers in this area founded a Roman Catholic community around 1510. In 1680, the Spanish passed Leyes de Indias. This law required parish churches to be located near the town square. Consequently, when construction began on the second Iglesis de San Germán de Auxerre eight years later, the new church became an anchor of Plaza Francisco Mariano Quiñones. The structure was extensively refurbished after earthquake damage in the 18th and 19th centuries. The bell tower was replaced in 1939.
