The Hospital of Five Wounds was established outside of the city walls in 1500. The name is a reference to the wounds received by Christ during His crucifixion. Less than 50 years later, Don Fadrique Enriquez of Ribera, 1st Marquis of Tarifa, was the benefactor for constructing a large, Andalusian Mannerism building to house the facility in the La Macarena neighborhood. Hospital de las Cinco Llagas vacated the property in the 1960s. After an extensive renovation, this became the headquarters for the Andalusian Parliament in 1992.