Cartagena is located in a large plain called Campo de Cartagena. The region is shaped by five mountains in the north, another five in the south and the Mediterranean Sea. The historic center of the city is further defined by hills. Cartagena also has a natural, deep-water port. The oval-shaped harbor is nestled in an inlet of Cartagena Bay. This combination of geological features has made Cartagena an attractive location for civilizations for over 2,500 years.